Prof. Dr. Mathias Hoehn

Gruppenleiter

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Curriculum Vitae

2015-2016	Incoming President, European Society for Molecular Imaging (President 2016-17)
2013-	Visiting professor, Leiden University Mecial Center, Leiden, NL
2010	NWO-Alexander-von-Humboldt fellow, sabbatical at Leiden University, NL
1997	Professor, tenured position at Max Planck Institute for Neurological Research, Cologne
1997	Habilitation in Experimental Neurology (with special reference to imaging techniques) University at Cologne
since 1987	Head of the In-vivo-NMR Laboratory at the Max Planck Institute for Neurological Research, Cologne
1985-1987	Senior scientist, Institute of Physiological Chemistry, RWTH-Klinikum Aachen, Head of the NMR-group
1984-1985	Post-doc (DFG-stipend), University of California, San Diego in La Jolla California, USA
1983-1984	Research fellow, Dept. Biology & Preclin. Medicine, University of Regensburg
1983	PhD in biophysics University of Regensburg
1979	Guest scientist (DAAD-stipend), Institute of Polymer Science, University of Massachusetts in Amherst, Mass., USA
1978-1979	Study of biology, University of Regensburg
1978	Diploma (M.S.), University of Regensburg
1975-1976	Study of physics, University of Colorado in Boulder, Colorado, USA
1972-1978	Study of physics (with mathematics, chemistry) University of Regensburg

Forschungsschwerpunkte

Stammzellbasierte Regeneration nach Hirnläsionen

Entwicklung von Molecular Imaging Verfahren zur Charakterisierung der Zelldynamik im Hirn
Strukturelle und funktionelle zerebrale Netzwerke im gesunden und pathologischen Zustand
Modulation und Wiederherstellung der Funktionalität durch spezifische Stammzellimplantationen: Differenzierung und Integration des Stammzell-Grafts
Rolle der Inflammation für die Regeneration: Modulation zwischen pro-inflammatorischer und anti-inflammatorischer (protektiver) Polarization

Publikationen

Human neural stem cell intracerebral grafts show spontaneous early neuronal differentiation after several weeks. Biomaterials 44, 143-154.
A. Tennstaedt, M. Aswendt, J. Adamczak, M. Selt, U. Collienne, G. Schneider, N. Henn, C. Schaefer, M. Lagouge, D. Wiedermann, P. Kloppenburg, M. Hoehn (2014)

Longitudinal bioluminescence imaging of VEGFR2 expression as a correlate for angiogenesis after middle cerebral artery occlusion. Frontiers of Cellular Neuroscience 8, 274.
J. Adamczak, G. Schneider, M. Nelles, I. Que, E. Suidgeest, L.v.d.Weerd, C. Löwik, M. Hoehn (2014)

A multimodality platform to image stem cell graft survival in the naïve and stroke-damaged mouse brain. Biomaterials, 35 2218-2226.
P. Boehm-Sturm, M. Aswendt, A. Minassian, S. Michalk, L. Mengler, J. Adamczak, L. Mezzanotte, C. Löwik, M. Hoehn (2014)

Boosting bioluminescence neuroimaging: an optimized protocol for brain studies. PLOS One 8, e55662.
M. Aswendt, J. Adamczak, S. Couillard-Despres, M. Hoehn (2013)

Reliability and spatial specificity of rat brain sensorimotor functional connectivity networks are superior under sedation compared with general anesthesia. NMR in Biomedicine 26, 638-650.
D. Kalthoff, C. Po, D. Wiedermann, M. Hoehn (2013)

White matter reorganization and functional recovery following transient focal cerebral ischemia in rats. PLOS One, 7, e45629.
C. Po, YB Kim, M. Nelles, D. Kalthoff, M. Hoehn (2012)

Connectivity of thalamo-cortical pathway in rat brain: combined diffusion spectrum imaging and fMRI at 11.7T. NMR in Biomedicine 25, 943-952.
YB Kim, D. Kalthoff, C. Po, D. Wiedermann, M. Hoehn (2012)

Stem cell mediation of functional recovery after stroke in the rat. PLoS One 5, e12779.
P. Ramos-Cabrer, C. Justicia, D. Wiedermann, M. Hoehn (2010)

In vivo optical imaging of neurogenesis: watching new neurons in the intact brain. Molecular Imaging 7, 28-34.
S. Couillard-Després, B. Winner, S. Plötz, D. Wiedermann, R. Aigner, U. Bogdahn, J. Winkler, M. Hoehn, L. Aigner (2008)

Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proceedings of the National Academy of Sciences USA, 99, 16267-16272.
M. Hoehn, E. Küstermann, J. Blunk, D. Wiedermann, T. Trapp, S. Wecker, M. Föcking, H. Arnold, J. Hescheler, B.K. Fleischmann, W. Schwindt, C. Bührle (2002)

UNIVERSITY OF COLOGNE

Faculty of MedicineNeuroscience

Prof. Dr. Mathias Hoehn

Gruppenleiter

Curriculum Vitae

Forschungsschwerpunkte